The corrected gene proximity map for analyzing the 3D genome organization using Hi-C data

The corrected gene proximity map for analyzing the 3D genome organization using Hi-C data

Abstract Background Genome-wide ligation-based assays such as Hi-C provide us with an unprecedented opportunity to investigate the spatial organization of the genome. Results of a typical Hi-C experiment are often summarized in a chromosomal contact map, a matrix whose elements reflect the co-locati...

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Bibliographic Details
Main Authors: Cheng Ye, Alberto Paccanaro, Mark Gerstein, Koon-Kiu Yan
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Bioinformatics
Subjects:
3D genome
Hi-C data analysis
Network modularity
Network theory
Online Access:http://link.springer.com/article/10.1186/s12859-020-03545-y

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http://link.springer.com/article/10.1186/s12859-020-03545-y

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