Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer.

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer.

The anti-tuberculosis-vaccine Bacillus Calmette-Guérin (BCG) is the most widely used vaccine in the world. In addition to its effects against tuberculosis, BCG vaccination also induces non-specific beneficial effects against certain forms of malignancy and against infections with unrelated pathogens...

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Bibliographic Details
Main Authors: Kathrin Buffen, Marije Oosting, Jessica Quintin, Aylwin Ng, Johanneke Kleinnijenhuis, Vinod Kumar, Esther van de Vosse, Cisca Wijmenga, Reinout van Crevel, Egbert Oosterwijk, Anne J Grotenhuis, Sita H Vermeulen, Lambertus A Kiemeney, Frank L van de Veerdonk, Georgios Chamilos, Ramnik J Xavier, Jos W M van der Meer, Mihai G Netea, Leo A B Joosten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4214925?pdf=render

Internet

http://europepmc.org/articles/PMC4214925?pdf=render

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