Reconstruction of ancestral RNA sequences under multiple structural constraints

Reconstruction of ancestral RNA sequences under multiple structural constraints

Abstract Background Secondary structures form the scaffold of multiple sequence alignment of non-coding RNA (ncRNA) families. An accurate reconstruction of ancestral ncRNAs must use this structural signal. However, the inference of ancestors of a single ncRNA family with a single consensus structure...

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Bibliographic Details
Main Authors: Olivier Tremblay-Savard, Vladimir Reinharz, Jérôme Waldispühl
Format: Article
Language:English
Published: BMC 2016-11-01
Series:BMC Genomics
Subjects:
RNA
Secondary structure
Ancestor reconstruction
Evolution
Phylogeny
Algorithm
Online Access:http://link.springer.com/article/10.1186/s12864-016-3105-4

Internet

http://link.springer.com/article/10.1186/s12864-016-3105-4

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