Reconstruction of ancestral RNA sequences under multiple structural constraints
Abstract Background Secondary structures form the scaffold of multiple sequence alignment of non-coding RNA (ncRNA) families. An accurate reconstruction of ancestral ncRNAs must use this structural signal. However, the inference of ancestors of a single ncRNA family with a single consensus structure...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2016-11-01
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| Series: | BMC Genomics |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12864-016-3105-4 |