The Antimicrobial Activity of Peripheral Blood Neutrophils Is Altered in Patients with Primary Ciliary Dyskinesia

The Antimicrobial Activity of Peripheral Blood Neutrophils Is Altered in Patients with Primary Ciliary Dyskinesia

The airways of patients with primary ciliary dyskinesia (PCD) contain persistently elevated neutrophil numbers and CXCL8 levels. Despite their abundance, neutrophils fail to clear the airways from bacterial infections. We investigated whether neutrophil functions are altered in patients with PCD. Ne...

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Bibliographic Details
Main Authors: Maaike Cockx, Marfa Blanter, Mieke Gouwy, Pieter Ruytinx, Sara Abouelasrar Salama, Sofie Knoops, Noëmie Pörtner, Lotte Vanbrabant, Natalie Lorent, Mieke Boon, Sofie Struyf
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
primary ciliary dyskinesia
neutrophils
antibacterial activity
Online Access:https://www.mdpi.com/1422-0067/22/12/6172

Internet

https://www.mdpi.com/1422-0067/22/12/6172

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