ApoA-II maintains HDL levels in part by inhibition of hepatic lipase: studies in apoA-II and hepatic lipase double knockout mice

ApoA-II maintains HDL levels in part by inhibition of hepatic lipase: studies in apoA-II and hepatic lipase double knockout mice

High density lipoprotein (HDL) cholesterol levels are inversely related to the risk of developing coronary heart disease. Apolipoprotein (apo) A-II is the second most abundant HDL apolipoprotein and apoA-II knockout mice show a 70% reduction in HDL cholesterol levels. There is also evidence, using h...

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Bibliographic Details
Main Authors: Wei Weng, Neal A. Brandenburg, Shaobin Zhong, Joanna Halkias, Lin Wu, Xian-cheng Jiang, Alan Tall, Jan L. Breslow
Format: Article
Language:English
Published: Elsevier 1999-06-01
Series:Journal of Lipid Research
Subjects:
apoA-II
apoA-I
hepatic lipase
HDL cholesterol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520335100

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http://www.sciencedirect.com/science/article/pii/S0022227520335100

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