Viral quasispecies assembly via maximal clique enumeration.

Viral quasispecies assembly via maximal clique enumeration.

Virus populations can display high genetic diversity within individual hosts. The intra-host collection of viral haplotypes, called viral quasispecies, is an important determinant of virulence, pathogenesis, and treatment outcome. We present HaploClique, a computational approach to reconstruct the s...

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Bibliographic Details
Main Authors: Armin Töpfer, Tobias Marschall, Rowena A Bull, Fabio Luciani, Alexander Schönhuth, Niko Beerenwinkel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24675810/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24675810/pdf/?tool=EBI

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