O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures

O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures

The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen Histoplasma capsulatum, elevated temperature is required for differentiation of mycelia or conidia into yeast cells, a step critical for invasion and replicati...

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Bibliographic Details
Main Authors: Andrew L. Garfoot, Kristie D. Goughenour, Marcel Wuthrich, Murugesan V. S. Rajaram, Larry S. Schlesinger, Bruce S. Klein, Chad A. Rappleye, J. Andrew Alspaugh
Format: Article
Language:English
Published: American Society for Microbiology 2018-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e02121-17

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http://mbio.asm.org/cgi/content/full/9/1/e02121-17

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