O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures
The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen Histoplasma capsulatum, elevated temperature is required for differentiation of mycelia or conidia into yeast cells, a step critical for invasion and replicati...
Main Authors: | Andrew L. Garfoot, Kristie D. Goughenour, Marcel Wuthrich, Murugesan V. S. Rajaram, Larry S. Schlesinger, Bruce S. Klein, Chad A. Rappleye, J. Andrew Alspaugh |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-01-01
|
Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/9/1/e02121-17 |
Similar Items
-
The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure
by: Andrew L. Garfoot, et al.
Published: (2016-04-01) -
Histoplasma capsulatum: Drugs and Sugars
by: Goughenour, Kristie
Published: (2020) -
Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress.
by: Brian H Youseff, et al.
Published: (2012-01-01) -
<i>Histoplasma</i> Responses to Nutritional Immunity Imposed by Macrophage Activation
by: Peter J. Brechting, et al.
Published: (2019-06-01) -
Reverse genetics through random mutagenesis in <it>Histoplasma capsulatum</it>
by: Rappleye Chad A, et al.
Published: (2009-11-01)