Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication.

Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication.

Kaposi's sarcoma herpesvirus (KSHV) causes Kaposi's sarcoma and certain lymphoproliferative malignancies. Latent infection is established in the majority of tumor cells, whereas lytic replication is reactivated in a small fraction of cells, which is important for both virus spread and dise...

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Main Authors: Giuseppe Balistreri, Johanna Viiliäinen, Mikko Turunen, Raquel Diaz, Lauri Lyly, Pirita Pekkonen, Juha Rantala, Krista Ojala, Grzegorz Sarek, Mari Teesalu, Oxana Denisova, Karita Peltonen, Ilkka Julkunen, Markku Varjosalo, Denis Kainov, Olli Kallioniemi, Marikki Laiho, Jussi Taipale, Sampsa Hautaniemi, Päivi M Ojala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005424

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https://doi.org/10.1371/journal.ppat.1005424

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