The Streptococcus pneumoniae pilus-1 displays a biphasic expression pattern.

The Streptococcus pneumoniae pilus-1 is encoded by pilus islet 1 (PI-1), which has three clonal variants (clade I, II and III) and is present in about 30% of clinical pneumococcal isolates. In vitro and in vivo assays have demonstrated that pilus-1 is involved in attachment to epithelial cells and v...

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Main Authors: Gabriella De Angelis, Monica Moschioni, Alessandro Muzzi, Alfredo Pezzicoli, Stefano Censini, Isabel Delany, Morena Lo Sapio, Antonia Sinisi, Claudio Donati, Vega Masignani, Michèle A Barocchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3120856?pdf=render