NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.

Burkholderia pseudomallei causes the tropical infection melioidosis. Pneumonia is a common manifestation of melioidosis and is associated with high mortality. Understanding the key elements of host defense is essential to developing new therapeutics for melioidosis. As a flagellated bacterium encodi...

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Bibliographic Details
Main Authors: T Eoin West, Nicolle D Myers, Narisara Chantratita, Wirongrong Chierakul, Direk Limmathurotsakul, Vanaporn Wuthiekanun, Edward A Miao, Adeline M Hajjar, Sharon J Peacock, H Denny Liggitt, Shawn J Skerrett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4169243?pdf=render