Effects of ethanol and acetaldehyde on tight junction integrity: in vitro study in a three dimensional intestinal epithelial cell culture model.

Effects of ethanol and acetaldehyde on tight junction integrity: in vitro study in a three dimensional intestinal epithelial cell culture model.

<h4>Background</h4>Intestinal barrier dysfunction and translocation of endotoxins are involved in the pathogenesis of alcoholic liver disease. Exposure to ethanol and its metabolite, acetaldehyde at relatively high concentrations have been shown to disrupt intestinal epithelial tight jun...

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Bibliographic Details
Main Authors: Elhaseen Elamin, Daisy Jonkers, Kati Juuti-Uusitalo, Sven van Ijzendoorn, Freddy Troost, Hans Duimel, Jos Broers, Fons Verheyen, Jan Dekker, Ad Masclee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22563376/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22563376/pdf/?tool=EBI

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