Epigenetic reprogramming and re-differentiation of a Ewing sarcoma cell line

Epigenetic reprogramming and re-differentiation of a Ewing sarcoma cell line

Developmental reprogramming techniques have been used to generate induced pluripotent stem (iPS) cells from both normal and malignant cells. The derivation of iPS cells from cancer has the potential to provide a unique scientific tool to overcome challenges associated with the establishment of cell...

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Bibliographic Details
Main Authors: Joseph Brady Moore IV, David M Loeb, Kyung U. Hong, Poul H Sorensen, Timothy J Triche, David W Lee, Michael eBarbato, Robert John Arceci
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Drug Resistance
Induced Pluripotent Stem Cells
epigenetics
Ewing sarcoma
reprogramming
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00015/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00015/full

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