Hematopoietic but not endothelial cell MyD88 contributes to host defense during gram-negative pneumonia derived sepsis.
Klebsiella pneumoniae is an important cause of sepsis. The common Toll-like receptor adapter myeloid differentiation primary response gene (MyD)88 is crucial for host defense against Klebsiella. Here we investigated the role of MyD88 in myeloid and endothelial cells during Klebsiella pneumosepsis. M...
Main Authors: | Miriam H P van Lieshout, Adam A Anas, Sandrine Florquin, Baidong Hou, Cornelis van't Veer, Alex F de Vos, Tom van der Poll |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-09-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4177915?pdf=render |
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