MIA-Sig: multiplex chromatin interaction analysis by signal processing and statistical algorithms

MIA-Sig: multiplex chromatin interaction analysis by signal processing and statistical algorithms

Abstract The single-molecule multiplex chromatin interaction data are generated by emerging 3D genome mapping technologies such as GAM, SPRITE, and ChIA-Drop. These datasets provide insights into high-dimensional chromatin organization, yet introduce new computational challenges. Thus, we developed...

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Bibliographic Details
Main Authors: Minji Kim, Meizhen Zheng, Simon Zhongyuan Tian, Byoungkoo Lee, Jeffrey H. Chuang, Yijun Ruan
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Genome Biology
Subjects:
3D genomics
Multiplex chromatin interactions
ChIA-Drop
Signal processing
Algorithms
Online Access:http://link.springer.com/article/10.1186/s13059-019-1868-z

Internet

http://link.springer.com/article/10.1186/s13059-019-1868-z

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