Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma
Abstract Background Genetic aberrations in hepatocellular carcinoma (HCC) are well known, but the functional consequences of such aberrations remain poorly understood. Results Here, we explored the effect of defined genetic changes on the transcriptome, proteome and phosphoproteome in twelve tumors...
Main Authors: | Christos Dimitrakopoulos, Sravanth Kumar Hindupur, Marco Colombi, Dritan Liko, Charlotte K. Y. Ng, Salvatore Piscuoglio, Jonas Behr, Ariane L. Moore, Jochen Singer, Hans-Joachim Ruscheweyh, Matthias S. Matter, Dirk Mossmann, Luigi M. Terracciano, Michael N. Hall, Niko Beerenwinkel |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-08-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12864-021-07876-9 |
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