The impact of indole-3-lactic acid on immature intestinal innate immunity and development: a transcriptomic analysis

Abstract An excessive intestinal inflammatory response may have a role in the pathogenesis of necrotizing enterocolitis (NEC) in very preterm infants. Indole-3-lactic acid (ILA) of breastmilk tryptophan was identified as the anti-inflammatory metabolite involved in probiotic conditioned media from B...

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Bibliographic Details
Main Authors: Wuyang Huang, Ky Young Cho, Di Meng, W. Allan Walker
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87353-1