Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids.

Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids.

Desmoid tumours (also called deep or aggressive fibromatoses) are potentially life-threatening fibromatous lesions. Hereditary desmoid tumours arise in individuals affected by either familial adenomatous polyposis (FAP) or hereditary desmoid disease (HDD) carrying germline mutations in APC. Most spo...

Full description

Bibliographic Details
Main Authors: Els Robanus-Maandag, Cathy Bosch, Saeid Amini-Nik, Jeroen Knijnenburg, Karoly Szuhai, Pascale Cervera, Raymond Poon, Diana Eccles, Paolo Radice, Marco Giovannini, Benjamin A Alman, Sabine Tejpar, Peter Devilee, Riccardo Fodde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3170296?pdf=render

Internet

http://europepmc.org/articles/PMC3170296?pdf=render

Similar Items