Absence of Regulatory T Cells Causes Phenotypic and Functional Switch in Murine Peritoneal Macrophages

Tissue macrophages are important components of tissue homeostasis and inflammatory pathologies. In the peritoneal cavity, resident macrophages interact with a variety of immune cells and can exhibit broad range of phenotypes and functions. Forkhead-box-P3 (FOXP3)+ regulatory T cells (Tregs) play an...

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Bibliographic Details
Main Authors: Jelena Skuljec, Adan Chari Jirmo, Anika Habener, Steven R. Talbot, Refik Pul, Ruth Grychtol, Malik Aydin, Christoph Kleinschnitz, Christine Happle, Gesine Hansen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02458/full