Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice

Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice

Obesity is a chronic inflammatory state characterized by infiltration of adipose tissue by immune cell populations, including T lymphocytes. Natural killer T (NKT) cells, a specialized lymphocyte subset recognizing lipid antigens, can be pro- or anti-inflammatory. Their role in adipose inflammation...

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Bibliographic Details
Main Authors: Savitha Subramanian, Michael S. Turner, Yilei Ding, Leela Goodspeed, Shari Wang, Jane H. Buckner, Kevin O'Brien, Godfrey S. Getz, Catherine A. Reardon, Alan Chait
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Journal of Lipid Research
Subjects:
lipids
antigens
adipose tissue
inflammation
steatosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353086

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http://www.sciencedirect.com/science/article/pii/S0022227520353086

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