10E,12Z-conjugated linoleic acid impairs adipocyte triglyceride storage by enhancing fatty acid oxidation, lipolysis, and mitochondrial reactive oxygen species

by Laura J. den Hartigh, Chang Yeop Han, Shari Wang, Mohamed Omer, Alan Chait
Published 2013-11-01

Aromatase deficiency in hematopoietic cells improves glucose tolerance in male mice through skeletal muscle-specific effects.

by Katya B Rubinow, Laura J den Hartigh, Leela Goodspeed, Shari Wang, Orhan K Oz
Published 2020-01-01

Serum amyloid A–containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties

by Chang Yeop Han, Inkyung Kang, Mohamed Omer, Shari Wang, Tomasz Wietecha, Thomas N. Wight, Alan Chait
Published 2020-10-01

Deficiency of Invariant Natural Killer T Cells Does Not Protect Against Obesity but Exacerbates Atherosclerosis in Ldlr−/− Mice

by Savitha Subramanian, Leela Goodspeed, Shari Wang, Yilei Ding, Kevin D. O’Brien, Godfrey S. Getz, Alan Chait, Catherine A. Reardon
Published 2018-02-01

Deletion of serum amyloid A3 improves high fat high sucrose diet-induced adipose tissue inflammation and hyperlipidemia in female mice.

by Laura J den Hartigh, Shari Wang, Leela Goodspeed, Yilei Ding, Michelle Averill, Savitha Subramanian, Tomasz Wietecha, Kevin D O'Brien, Alan Chait
Published 2014-01-01

Androgen receptor deficiency in monocytes/macrophages does not alter adiposity or glucose homeostasis in male mice

by Katya B Rubinow, Barbara Houston, Shari Wang, Leela Goodspeed, Kayoko Ogimoto, Gregory J Morton, Christopher McCarty, Robert E Braun, Stephanie T Page
Published 2018-01-01

Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice

by Savitha Subramanian, Michael S. Turner, Yilei Ding, Leela Goodspeed, Shari Wang, Jane H. Buckner, Kevin O'Brien, Godfrey S. Getz, Catherine A. Reardon, Alan Chait
Published 2013-10-01

10,12 Conjugated Linoleic Acid-Driven Weight Loss Is Protective against Atherosclerosis in Mice and Is Associated with Alternative Macrophage Enrichment in Perivascular Adipose Tis...

by Jenny E. Kanter, Leela Goodspeed, Shari Wang, Farah Kramer, Tomasz Wietecha, Diego Gomes-Kjerulf, Savitha Subramanian, Kevin D. O’Brien, Laura J. den Hartigh
Published 2018-10-01

Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammation

by Tomio Umemoto, Savitha Subramanian, Yilei Ding, Leela Goodspeed, Shari Wang, Chang Yeop Han, Antonio Sta. Teresa, Jinkyu Kim, Kevin D. O'Brien, Alan Chait
Published 2012-11-01

The apolipoprotein-AI mimetic peptide L4F at a modest dose does not attenuate weight gain, inflammation, or atherosclerosis in LDLR-null mice.

by Michelle M Averill, Eung Ju Kim, Leela Goodspeed, Shari Wang, Savitha Subramanian, Laura J Den Hartigh, Chongren Tang, Yilei Ding, Catherine A Reardon, Godfrey S Getz, Alan Chait
Published 2014-01-01

Serum amyloid A3 does not contribute to circulating SAA levels

by Tsuyoshi Chiba, Chang Yeop Han, Tomas Vaisar, Kentaro Shimokado, Atil Kargi, Mei-Hsiu Chen, Shari Wang, Thomas O. McDonald, Kevin D. O'Brien, Jay W Heinecke, Alan Chait
Published 2009-07-01

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

by Savitha Subramanian, Leela Goodspeed, Shari Wang, Jinkyu Kim, Lixia Zeng, George N. Ioannou, W. Geoffrey Haigh, Matthew M. Yeh, Kris V. Kowdley, Kevin D. O'Brien, Subramaniam Pennathur, Alan Chait
Published 2011-09-01

Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice.

by Laura J den Hartigh, Shari Wang, Leela Goodspeed, Tomasz Wietecha, Barbara Houston, Mohamed Omer, Kayoko Ogimoto, Savitha Subramanian, G A Nagana Gowda, Kevin D O'Brien, Karl J Kaiyala, Gregory J Morton, Alan Chait
Published 2017-01-01

T cell activation inhibitors reduce CD8+ T cell and pro-inflammatory macrophage accumulation in adipose tissue of obese mice.

by Vince N Montes, Michael S Turner, Savitha Subramanian, Yilei Ding, Martha Hayden-Ledbetter, Sonya Slater, Leela Goodspeed, Shari Wang, Mohamed Omer, Laura J Den Hartigh, Michelle M Averill, Kevin D O'Brien, Jeffrey Ledbetter, Alan Chait
Published 2013-01-01

Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity

by Chang Yeop Han, Inkyung Kang, Ingrid A. Harten, John A. Gebe, Christina K. Chan, Mohamed Omer, Kimberly M. Alonge, Laura J. den Hartigh, Diego Gomes Kjerulf, Leela Goodspeed, Savitha Subramanian, Shari Wang, Francis Kim, David E. Birk, Thomas N. Wight, Alan Chait
Published 2020-06-01