Deficiency of Invariant Natural Killer T Cells Does Not Protect Against Obesity but Exacerbates Atherosclerosis in Ldlr−/− Mice

by Savitha Subramanian, Leela Goodspeed, Shari Wang, Yilei Ding, Kevin D. O’Brien, Godfrey S. Getz, Alan Chait, Catherine A. Reardon
Published 2018-02-01

Deletion of serum amyloid A3 improves high fat high sucrose diet-induced adipose tissue inflammation and hyperlipidemia in female mice.

by Laura J den Hartigh, Shari Wang, Leela Goodspeed, Yilei Ding, Michelle Averill, Savitha Subramanian, Tomasz Wietecha, Kevin D O'Brien, Alan Chait
Published 2014-01-01

Effects of Combined Oxytocin and Beta-3 Receptor Agonist (CL 316243) Treatment on Body Weight and Adiposity in Male Diet-Induced Obese Rats

by Melise M. Edwards, Ha K. Nguyen, Andrew D. Dodson, Adam J. Herbertson, Tomasz A. Wietecha, Tomasz A. Wietecha, Tami Wolden-Hanson, James L. Graham, Mackenzie K. Honeycutt, Jared D. Slattery, Kevin D. O’Brien, Kevin D. O’Brien, Peter J. Havel, Peter J. Havel, James E. Blevins, James E. Blevins
Published 2021-09-01

10,12 Conjugated Linoleic Acid-Driven Weight Loss Is Protective against Atherosclerosis in Mice and Is Associated with Alternative Macrophage Enrichment in Perivascular Adipose Tis...

by Jenny E. Kanter, Leela Goodspeed, Shari Wang, Farah Kramer, Tomasz Wietecha, Diego Gomes-Kjerulf, Savitha Subramanian, Kevin D. O’Brien, Laura J. den Hartigh
Published 2018-10-01

Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammation

by Tomio Umemoto, Savitha Subramanian, Yilei Ding, Leela Goodspeed, Shari Wang, Chang Yeop Han, Antonio Sta. Teresa, Jinkyu Kim, Kevin D. O'Brien, Alan Chait
Published 2012-11-01

An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers.

by Sophia E Airhart, Laura M Shireman, Linda J Risler, Gail D Anderson, G A Nagana Gowda, Daniel Raftery, Rong Tian, Danny D Shen, Kevin D O'Brien
Published 2017-01-01

Serum amyloid P colocalizes with apolipoproteins in human atheroma: functional implicationss⃞

by Cameron R. Stewart, Antonio Haw, III, Roland Lopez, Thomas O. McDonald, Judy M. Callaghan, Malcolm J. McConville, Kathryn J. Moore, Geoffrey J. Howlett, Kevin D. O'Brien
Published 2007-10-01

Serum amyloid A3 does not contribute to circulating SAA levels

by Tsuyoshi Chiba, Chang Yeop Han, Tomas Vaisar, Kentaro Shimokado, Atil Kargi, Mei-Hsiu Chen, Shari Wang, Thomas O. McDonald, Kevin D. O'Brien, Jay W Heinecke, Alan Chait
Published 2009-07-01

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

by Savitha Subramanian, Leela Goodspeed, Shari Wang, Jinkyu Kim, Lixia Zeng, George N. Ioannou, W. Geoffrey Haigh, Matthew M. Yeh, Kris V. Kowdley, Kevin D. O'Brien, Subramaniam Pennathur, Alan Chait
Published 2011-09-01

Summary of clinical and laboratory data of study subjects with and without DCE-MRI plaque measurements in the AIM-HIGH clinical trial

by Kevin D. O’Brien, Daniel S. Hippe, Huijun Chen, Moni B. Neradilek, Jeffrey L. Probstfield, Suzanne Peck, Daniel A. Isquith, Gador Canton, Chun Yuan, Nayak L. Polissar, Xue-Qiao Zhao, William S. Kerwin
Published 2016-03-01

Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice.

by Laura J den Hartigh, Shari Wang, Leela Goodspeed, Tomasz Wietecha, Barbara Houston, Mohamed Omer, Kayoko Ogimoto, Savitha Subramanian, G A Nagana Gowda, Kevin D O'Brien, Karl J Kaiyala, Gregory J Morton, Alan Chait
Published 2017-01-01

T cell activation inhibitors reduce CD8+ T cell and pro-inflammatory macrophage accumulation in adipose tissue of obese mice.

by Vince N Montes, Michael S Turner, Savitha Subramanian, Yilei Ding, Martha Hayden-Ledbetter, Sonya Slater, Leela Goodspeed, Shari Wang, Mohamed Omer, Laura J Den Hartigh, Michelle M Averill, Kevin D O'Brien, Jeffrey Ledbetter, Alan Chait
Published 2013-01-01

Testing the Role of Myeloid Cell Glucose Flux in Inflammation and Atherosclerosis

by Tomohiro Nishizawa, Jenny E. Kanter, Farah Kramer, Shelley Barnhart, Xia Shen, Anuradha Vivekanandan-Giri, Valerie Z. Wall, Jason Kowitz, Sridevi Devaraj, Kevin D. O’Brien, Subramaniam Pennathur, Jingjing Tang, Robert S. Miyaoka, Elaine W. Raines, Karin E. Bornfeldt
Published 2014-04-01

Accuracy of Doppler blood pressure measurement in HeartMate 3 ventricular assist device patients

by Song Li, Jennifer A. Beckman, Nathan G. Welch, Richard K. Cheng, Sunny W. Rockom, Wayne C. Levy, Kevin D. O'Brien, Todd F. Dardas, Shin Lin, Peter J. Leary, James Kirkpatrick, James M. McCabe, Jason Bjelkengren, Fanette Chassagne, Alberto Aliseda, Daniel Zimpfer, Claudius Mahr
Published 2020-12-01

Accuracy of Doppler blood pressure measurement in continuous‐flow left ventricular assist device patients

by Song Li, Jennifer A. Beckman, Nathan G. Welch, Jason Bjelkengren, Sofia Carolina Masri, Elina Minami, April Stempien‐Otero, Wayne C. Levy, Kevin D. O'Brien, Shin Lin, Stephen D. Farris, Richard K. Cheng, Gregory Wood, Kevin Koomalsingh, James Kirkpatrick, James McCabe, Peter J. Leary, Fanette Chassagne, Venkat Keshav Chivukula, Alberto Aliseda, Claudius Mahr
Published 2019-08-01