Dopamine Augmented Rehabilitation in Stroke (DARS): a multicentre double-blind, randomised controlled trial of co-careldopa compared with placebo, in addition to routine NHS occupational and physical therapy, delivered early after stroke on functional recovery

Dopamine Augmented Rehabilitation in Stroke (DARS): a multicentre double-blind, randomised controlled trial of co-careldopa compared with placebo, in addition to routine NHS occupational and physical therapy, delivered early after stroke on functional recovery

Background: Dopamine is a key modulator of striatal function and learning, and may improve motor recovery after stroke. Seven small trials of dopamine agonists after stroke have provided equivocal evidence of the clinical effectiveness of dopamine agonists in improving motor recovery. Design: Dopami...

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Bibliographic Details
Main Authors: Gary A Ford, Bipin B Bhakta, Alastair Cozens, Bonnie Cundill, Suzanne Hartley, Ivana Holloway, David Meads, John Pearn, Sharon Ruddock, Catherine M Sackley, Eirini-Christina Saloniki, Gillian Santorelli, Marion F Walker, Amanda J Farrin
Format: Article
Language:English
Published: NIHR Journals Library 2019-07-01
Series:Efficacy and Mechanism Evaluation
Subjects:
STROKE
REHABILITATION
L-DOPA
MOBILITY
RECOVERY
DOUBLE-BLIND
PLACEBO
RCT
Online Access:https://doi.org/10.3310/eme06050

Internet

https://doi.org/10.3310/eme06050

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