Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes

Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes

The role of genetic risk markers for Alzheimer’s disease (AD) in mediating the neurocognitive endophenotypes (NEs) of subjects with mild cognitive impairment (MCI) has rarely been studied. The aim of the present study was to investigate the relationship between well-known AD-associated single-nucleo...

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Main Authors: Ana Espinosa, Begoña Hernández-Olasagarre, Sonia Moreno-Grau, Luca Kleineidam, Stefanie Heilmann-Heimbach, Isabel Hernández, Steffen Wolfsgruber, Holger Wagner, Maitée Rosende-Roca, Ana Mauleón, Liliana Vargas, Asunción Lafuente, Octavio Rodríguez-Gómez, Carla Abdelnour, Silvia Gil, Marta Marquié, Miguel A. Santos-Santos, Ángela Sanabria, Gemma Ortega, Gemma Monté-Rubio, Alba Pérez, Marta Ibarria, Susana Ruiz, Johannes Kornhuber, Oliver Peters, Lutz Frölich, Michael Hüll, Jens Wiltfang, Tobias Luck, Steffi Riedel-Heller, Laura Montrreal, Pilar Cañabate, Mariola Moreno, Silvia Preckler, Nuria Aguilera, Itziar de Rojas, Adelina Orellana, Montserrat Alegret, Sergi Valero, Markus M. Nöthen, Michael Wagner, Frank Jessen, Lluis Tárraga, Mercè Boada, Alfredo Ramírez, Agustín Ruiz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
mild cognitive impairment
neurocognitive endophenotypes
genome-wide association studies
single-nucleotide polymorphism
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00340/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00340/full

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