The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities

The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities

DYRK (dual-specificity tyrosine-regulated kinases) are an evolutionary conserved family of protein kinases with members from yeast to humans. In humans, DYRKs are pleiotropic factors that phosphorylate a broad set of proteins involved in many different cellular processes. These include factors that...

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Bibliographic Details
Main Authors: Jacopo Boni, Carlota Rubio-Perez, Nuria López-Bigas, Cristina Fillat, Susana de la Luna
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
DYRK kinases
cellular signaling
expression dysregulation
cell cycle
cell survival
tumor progression
Online Access:https://www.mdpi.com/2072-6694/12/8/2106

Internet

https://www.mdpi.com/2072-6694/12/8/2106

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