Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function.

Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function.

Oxidative stress is involved in the pathogenesis of airway obstruction in α1-antitrypsin deficient patients. This may result in a shortening of telomere length, resulting in cellular senescence. To test whether telomere length differs in α1-antitrypsin deficient patients compared with controls, we m...

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Bibliographic Details
Main Authors: Aabida Saferali, Jee Lee, Don D Sin, Farshid N Rouhani, Mark L Brantly, Andrew J Sandford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3998943?pdf=render

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http://europepmc.org/articles/PMC3998943?pdf=render

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