TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

Background & Aims: HDV infection induces the most severe form of human viral hepatitis. However, the specific reasons for the severity of the disease remain unknown. Recently, we developed an HDV replication mouse model in which, for the first time, liver damage was detected. Methods: HDV an...

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Bibliographic Details
Main Authors: Carla Usai, Sheila Maestro, Gracian Camps, Cristina Olague, Lester Suárez-Amaran, Africa Vales, Tomas Aragon, Mirja Hommel, Rafael Aldabe, Gloria Gonzalez-Aseguinolaza
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:JHEP Reports
Subjects:
HDV
liver injury
TNF-α
Etanercept
Antigens
Hepatitis Delta virus
Online Access:http://www.sciencedirect.com/science/article/pii/S258955592030032X

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http://www.sciencedirect.com/science/article/pii/S258955592030032X

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