Rich RNA Structure Landscapes Revealed by Mutate-and-Map Analysis.

Landscapes exhibiting multiple secondary structures arise in natural RNA molecules that modulate gene expression, protein synthesis, and viral infection [corrected]. We report herein that high-throughput chemical experiments can isolate an RNA's multiple alternative secondary structures as they...

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Bibliographic Details
Main Authors: Pablo Cordero, Rhiju Das
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004473