Automated in vivo platform for the discovery of functional food treatments of hypercholesterolemia.

The zebrafish is becoming an increasingly popular model system for both automated drug discovery and investigating hypercholesterolemia. Here we combine these aspects and for the first time develop an automated high-content confocal assay for treatments of hypercholesterolemia. We also create two al...

Full description

Bibliographic Details
Main Authors: Robert M Littleton, Kevin J Haworth, Hong Tang, Kenneth D R Setchell, Sandra Nelson, Jay R Hove
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3549914?pdf=render