Antigen-specific monoclonal antibodies isolated from B cells expressing constitutively active STAT5.

Antigen-specific monoclonal antibodies isolated from B cells expressing constitutively active STAT5.

BACKGROUND: Fully human monoclonal antibodies directed against specific pathogens have a high therapeutic potential, but are difficult to generate. METHODOLOGY/PRINCIPAL FINDINGS: Memory B cells were immortalized by expressing an inducible active mutant of the transcription factor Signal Transducer...

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Bibliographic Details
Main Authors: Ferenc A Scheeren, Caroline M M van Geelen, Etsuko Yasuda, Hergen Spits, Tim Beaumont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3078118?pdf=render

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http://europepmc.org/articles/PMC3078118?pdf=render

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