Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

Recombination, the exchange of information between different genetic polymer strands, is of fundamental importance in biology for genome maintenance and genetic diversification and is mediated by dedicated recombinase enzymes. Here, we describe an innate capacity for non-enzymatic recombination (and...

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Bibliographic Details
Main Authors: Hannes Mutschler, Alexander I Taylor, Benjamin T Porebski, Alice Lightowlers, Gillian Houlihan, Mikhail Abramov, Piet Herdewijn, Philipp Holliger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-11-01
Series:eLife
Subjects:
nucleic acids
RNA
recombination
ligation
non-enzymatic
origin of life
Online Access:https://elifesciences.org/articles/43022

Internet

https://elifesciences.org/articles/43022

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