Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

Objectives: Obesity is a complex disease associated with a high risk of comorbidities. Gastric bypass surgery, an invasive procedure with low patient eligibility, is currently the most effective intervention that achieves sustained weight loss. This beneficial effect is attributed to alterations in...

Full description

Bibliographic Details
Main Authors: Kaare V. Grunddal, Thi A. Diep, Natalia Petersen, Iain R. Tough, Louise J. Skov, Lingzhi Liu, Jesse A. Buijink, Franziska Mende, Chunyu Jin, Sara L. Jepsen, Louis M.E. Sørensen, Michael P. Achiam, Rune B. Strandby, Anders Bach, Bolette Hartmann, Thomas M. Frimurer, Siv A. Hjorth, Michel Bouvier, Helen Cox, Birgitte Holst
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Molecular Metabolism
Subjects:
GPR39 agonist
Enteroendocrine cells
Gut hormone secretion
Glucagon-like peptide-1
Obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821000478

Internet

http://www.sciencedirect.com/science/article/pii/S2212877821000478

Similar Items