Rapid 16S rRNA next-generation sequencing of polymicrobial clinical samples for diagnosis of complex bacterial infections.

Rapid 16S rRNA next-generation sequencing of polymicrobial clinical samples for diagnosis of complex bacterial infections.

Classifying individual bacterial species comprising complex, polymicrobial patient specimens remains a challenge for culture-based and molecular microbiology techniques in common clinical use. We therefore adapted practices from metagenomics research to rapidly catalog the bacterial composition of c...

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Bibliographic Details
Main Authors: Stephen J Salipante, Dhruba J Sengupta, Christopher Rosenthal, Gina Costa, Jessica Spangler, Elizabeth H Sims, Michael A Jacobs, Samuel I Miller, Daniel R Hoogestraat, Brad T Cookson, Connor McCoy, Frederick A Matsen, Jay Shendure, Clarence C Lee, Timothy T Harkins, Noah G Hoffman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23734239/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23734239/?tool=EBI

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