Transcriptional Elongation Factor Elongin A Regulates Retinoic Acid-Induced Gene Expression during Neuronal Differentiation

Transcriptional Elongation Factor Elongin A Regulates Retinoic Acid-Induced Gene Expression during Neuronal Differentiation

Elongin A increases the rate of RNA polymerase II (pol II) transcript elongation by suppressing transient pausing by the enzyme. Elongin A also acts as a component of a cullin-RING ligase that can target stalled pol II for ubiquitylation and proteasome-dependent degradation. It is not known whether...

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Bibliographic Details
Main Authors: Takashi Yasukawa, Shachi Bhatt, Tamotsu Takeuchi, Junya Kawauchi, Hidehisa Takahashi, Aya Tsutsui, Takuya Muraoka, Makoto Inoue, Masayuki Tsuda, Shigetaka Kitajima, Ronald C. Conaway, Joan W. Conaway, Paul A. Trainor, Teijiro Aso
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712003361

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http://www.sciencedirect.com/science/article/pii/S2211124712003361

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