Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection.
Natural Killer (NK) cells contribute to the control of viral infection by directly killing target cells and mediating cytokine release. In C57BL/6 mice, the Ly49H activating NK cell receptor plays a key role in early resistance to mouse cytomegalovirus (MCMV) infection through specific recognition o...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-12-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4256466?pdf=render |