Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection.

Natural Killer (NK) cells contribute to the control of viral infection by directly killing target cells and mediating cytokine release. In C57BL/6 mice, the Ly49H activating NK cell receptor plays a key role in early resistance to mouse cytomegalovirus (MCMV) infection through specific recognition o...

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Bibliographic Details
Main Authors: Nassima Fodil, David Langlais, Peter Moussa, Gregory Allan Boivin, Tania Di Pietrantonio, Irena Radovanovic, Anne Dumaine, Mathieu Blanchette, Erwin Schurr, Philippe Gros, Silvia Marina Vidal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4256466?pdf=render