Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies

Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies

Virotherapy research involves the development, exploration, and application of oncolytic viruses that combine direct killing of cancer cells by viral infection, replication, and spread (oncolysis) with indirect killing by induction of anti-tumor immune responses. Oncolytic viruses can also be engine...

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Bibliographic Details
Main Authors: Dirk M. Nettelbeck, Mathias F. Leber, Jennifer Altomonte, Assia Angelova, Julia Beil, Susanne Berchtold, Maike Delic, Jürgen Eberle, Anja Ehrhardt, Christine E. Engeland, Henry Fechner, Karsten Geletneky, Katrin Goepfert, Per Sonne Holm, Stefan Kochanek, Florian Kreppel, Lea Krutzke, Florian Kühnel, Karl Sebastian Lang, Antonio Marchini, Markus Moehler, Michael D. Mühlebach, Ulrike Naumann, Roman Nawroth, Jürg Nüesch, Jean Rommelaere, Ulrich M. Lauer, Guy Ungerechts
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
oncolytic virus
virotherapy
research in Germany
virus engineering
virus targeting
therapeutic transgene
Online Access:https://www.mdpi.com/1999-4915/13/8/1420

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https://www.mdpi.com/1999-4915/13/8/1420

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