Plasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRh2a and b binding domains.

Plasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRh2a and b binding domains.

Plasmodium falciparum, the causative agent of the most severe form of malaria in humans invades erythrocytes using multiple ligand-receptor interactions. The P. falciparum reticulocyte binding-like homologue proteins (PfRh or PfRBL) are important for entry of the invasive merozoite form of the paras...

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Bibliographic Details
Main Authors: Tony Triglia, Lin Chen, Sash Lopaticki, Chaitali Dekiwadia, David T Riglar, Anthony N Hodder, Stuart A Ralph, Jake Baum, Alan F Cowman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3116812?pdf=render

Internet

http://europepmc.org/articles/PMC3116812?pdf=render

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