Impact of Interleukin 10 Deficiency on Intestinal Epithelium Responses to Inflammatory Signals

Impact of Interleukin 10 Deficiency on Intestinal Epithelium Responses to Inflammatory Signals

Interleukin 10 (IL-10) is a pleiotropic, anti-inflammatory cytokine that has a major protective role in the intestine. Although its production by cells of the innate and adaptive immune system has been extensively studied, its intrinsic role in intestinal epithelial cells is poorly understood. In th...

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Bibliographic Details
Main Authors: Stamatia Papoutsopoulou, Liam Pollock, Catherine Walker, William Tench, Sakim Shakh Samad, François Bergey, Luca Lenzi, Raheleh Sheibani-Tezerji, Phillip Rosenstiel, Mohammad Tauqeer Alam, Vitor A. P. Martins Dos Santos, Werner Müller, Barry J. Campbell
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
intestine
enteroids
interleukin 10
tumour necrosis factor
NFκB
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.690817/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.690817/full

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