Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models

Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models

Inflammation is a growing area of research in neurodegeneration. In Huntington's disease (HD), a fatal inherited neurodegenerative disease caused by a CAG-repeat expansion in the gene encoding huntingtin, patients have increased plasma levels of inflammatory cytokines and circulating monocytes...

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Bibliographic Details
Main Authors: Ulrike Träger, Ralph Andre, Anna Magnusson-Lind, James R.C. Miller, Colúm Connolly, Andreas Weiss, Stephan Grueninger, Edina Silajdžić, Donna L. Smith, Blair R. Leavitt, Gillian P. Bates, Maria Björkqvist, Sarah J. Tabrizi
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Neurobiology of Disease
Subjects:
Huntington's disease
Neurodegeneration
Neuroinflammation
Innate immune system
Myeloid cells
Cytokines
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114003258

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http://www.sciencedirect.com/science/article/pii/S0969996114003258

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