An O antigen capsule modulates bacterial pathogenesis in Shigella sonnei.

Shigella is the leading cause for dysentery worldwide. Together with several virulence factors employed for invasion, the presence and length of the O antigen (OAg) of the lipopolysaccharide (LPS) plays a key role in pathogenesis. S. flexneri 2a has a bimodal OAg chain length distribution regulated...

Full description

Bibliographic Details
Main Authors: Mariaelena Caboni, Thierry Pédron, Omar Rossi, David Goulding, Derek Pickard, Francesco Citiulo, Calman A MacLennan, Gordon Dougan, Nicholas R Thomson, Allan Saul, Philippe J Sansonetti, Christiane Gerke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4368438?pdf=render