Whole-genome and targeted sequencing of drug-resistant Mycobacterium tuberculosis on the iSeq100 and MiSeq: A performance, ease-of-use, and cost evaluation.

<h4>Background</h4>Accurate, comprehensive, and timely detection of drug-resistant tuberculosis (TB) is essential to inform patient treatment and enable public health surveillance. This is crucial for effective control of TB globally. Whole-genome sequencing (WGS) and targeted next-gener...

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Main Authors: Rebecca E Colman, Aurélien Mace, Marva Seifert, Jonathan Hetzel, Haifa Mshaiel, Anita Suresh, Darrin Lemmer, David M Engelthaler, Donald G Catanzaro, Amanda G Young, Claudia M Denkinger, Timothy C Rodwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002794