Plasticity of Synaptic Transmission in Human Stem Cell-Derived Neural Networks

Summary: Long-term potentiation and depression, inferred from analysis on brain slices, are considered the cellular processes underlying learning and memory formation. They have not so far been demonstrated in human stem cell-derived neurons. By expressing channelrhodopsin in hESCs-derived glutamate...

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Bibliographic Details
Main Authors: Yi Dong, Man Xiong, Yuejun Chen, Yezheng Tao, Xiang Li, Anita Bhattacharyya, Su-Chun Zhang
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220300122