Abnormal Expression of YAP Is Associated With Proliferation, Differentiation, Neutrophil Infiltration, and Adverse Outcome in Patients With Nasal Inverted Papilloma

Abnormal Expression of YAP Is Associated With Proliferation, Differentiation, Neutrophil Infiltration, and Adverse Outcome in Patients With Nasal Inverted Papilloma

BackgroundNasal inverted papilloma (NIP) is a common benign tumor. Yes-associated protein (YAP) is the core effector molecule of the Hippo pathway, which regulates the proliferation and differentiation of airway epithelium. While its role in proliferation may be connected to NIP formation, no defini...

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Main Authors: Tian Yuan, Rui Zheng, Xiang-min Zhou, Peng Jin, Zhi-qun Huang, Xiao-xue Zi, Qing-wu Wu, Wei-hao Wang, Hui-yi Deng, Wei-feng Kong, Hui-jun Qiu, Sui-zi Zhou, Qian-min Chen, Yan-yi Tu, Tao Li, Jing Liu, Kai Sen Tan, Hsiao Hui Ong, Li Shi, Zhuang-gui Chen, Xue-kun Huang, Qin-tai Yang, De-yun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
nasal inverted papilloma
yes-associated protein
epithelial cells
proliferation
differentiation
neutrophils
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.625251/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.625251/full

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