The chemokine receptor CXCR4 strongly promotes neuroblastoma primary tumour and metastatic growth, but not invasion.

Neuroblastoma (NB) is a heterogeneous, and particularly malignant childhood neoplasm in its higher stages, with a propensity to form metastasis in selected organs, in particular liver and bone marrow, and for which there is still no efficient treatment available beyond surgery. Recent evidence indic...

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Bibliographic Details
Main Authors: Roland Meier, Annick Mühlethaler-Mottet, Marjorie Flahaut, Aurélie Coulon, Carlo Fusco, Fawzia Louache, Katya Auderset, Katia Balmas Bourloud, Estelle Daudigeos, Curzio Ruegg, Gilles Vassal, Nicole Gross, Jean-Marc Joseph
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1995764?pdf=render