Post-translational control of RIPK3 and MLKL mediated necroptotic cell death [version 1; referees: 4 approved]

Several programmed lytic and necrotic-like cell death mechanisms have now been uncovered, including the recently described receptor interacting protein kinase-3 (RIPK3)-mixed lineage kinase domain-like (MLKL)-dependent necroptosis pathway. Genetic experiments have shown that programmed necrosis, inc...

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Bibliographic Details
Main Authors: James M. Murphy, James E. Vince
Format: Article
Language:English
Published: F1000 Research Ltd 2015-11-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/4-1297/v1