Germline Genetic Variants of the Renin-Angiotensin System, Hypoxia and Angiogenesis in Non-Small Cell Lung Cancer Progression: Discovery and Validation Studies

Germline Genetic Variants of the Renin-Angiotensin System, Hypoxia and Angiogenesis in Non-Small Cell Lung Cancer Progression: Discovery and Validation Studies

Introduction: The renin–angiotensin system (RAS) is involved in cell proliferation, immunoinflammatory response, hypoxia and angiogenesis, which are critical biological processes in lung cancer. Our aim was to study the association of putatively functional genetic polymorphisms in genes coding for p...

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Bibliographic Details
Main Authors: Maria Joana Catarata, Rui Medeiros, Maria José Oliveira, Alice Pêgo, João Gonçalo Frade, Maria Fátima Martins, Carlos Robalo Cordeiro, Felix J F Herth, Michael Thomas, Mark Kriegsmann, Michael Meister, Marc A Schneider, Thomas Muley, Ricardo Ribeiro
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
genetic polymorphisms
lung cancer
renin–angiotensin
hypoxia
angiogenesis
Online Access:https://www.mdpi.com/2072-6694/12/12/3834

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https://www.mdpi.com/2072-6694/12/12/3834

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