A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG.

A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG.

Class IC antiarrhythmic agents may induce acquired forms of Brugada Syndrome. We have identified a novel mutation in SCN5A, the gene that encodes the α-subunit of the human cardiac sodium channel (hNav1.5), in a patient who exhibited Brugada- type ECG changes during pharmacotherapy of atrial arrhyth...

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Bibliographic Details
Main Authors: Isik Turker, Takeru Makiyama, Matteo Vatta, Hideki Itoh, Takeshi Ueyama, Akihiko Shimizu, Tomohiko Ai, Minoru Horie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4999187?pdf=render

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http://europepmc.org/articles/PMC4999187?pdf=render

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