Targeting B cells in the pre-phase of systemic autoimmunity globally interferes with autoimmune pathology

Summary: Systemic lupus erythematosus (SLE) is characterized by a loss of self-tolerance, systemic inflammation, and multi-organ damage. While a variety of therapeutic interventions are available, it has become clear that an early diagnosis and treatment may be key to achieve long lasting therapeuti...

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Bibliographic Details
Main Authors: Anja Werner, Simon Schäfer, Olga Zaytseva, Heike Albert, Anja Lux, Jasminka Krištić, Marija Pezer, Gordan Lauc, Thomas Winkler, Falk Nimmerjahn
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221010440