Rapid host defense against Aspergillus fumigatus involves alveolar macrophages with a predominance of alternatively activated phenotype.

The ubiquitous fungus Aspergillus fumigatus is associated with chronic diseases such as invasive pulmonary aspergillosis in immunosuppressed patients and allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis or severe asthma. Because of constant exposure to this fungus, it...

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Main Authors: Shikha Bhatia, Mingjian Fei, Manohar Yarlagadda, Zengbiao Qi, Shizuo Akira, Shinobu Saijo, Yoichiro Iwakura, Nico van Rooijen, Gregory A Gibson, Claudette M St Croix, Anuradha Ray, Prabir Ray
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3016416?pdf=render